Michael A Carducci Selected Research

piritrexim

3/2008

Phase II open-label study of oral piritrexim in patients with advanced carcinoma of the urothelium who have experienced failure with standard chemotherapy.

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Michael A Carducci Research Topics

Disease

146	Prostatic Neoplasms (Prostate Cancer) 10/2022 - 05/2002
89	Neoplasms (Cancer) 12/2021 - 04/2002
32	Neoplasm Metastasis (Metastasis) 04/2022 - 10/2003
21	Renal Cell Carcinoma (Grawitz Tumor) 10/2019 - 01/2004
18	Disease Progression 01/2022 - 03/2003
15	Pain (Aches) 08/2021 - 04/2002
8	Fatigue 01/2022 - 07/2006
8	Carcinoma (Carcinomatosis) 01/2020 - 03/2002
7	Circulating Neoplastic Cells 07/2017 - 01/2013
6	Hypertension (High Blood Pressure) 10/2019 - 08/2006
6	Adenocarcinoma 01/2011 - 04/2002
4	Hypoxia (Hypoxemia) 03/2017 - 01/2011
4	Diarrhea 06/2013 - 01/2004
4	Neutropenia 10/2010 - 09/2003
3	Nausea 01/2022 - 08/2006
3	Chronic Disease (Chronic Diseases) 10/2018 - 12/2015
3	Heart Failure 12/2015 - 08/2006
3	Bone Resorption 04/2013 - 03/2003
3	Carcinogenesis 10/2011 - 08/2006
3	Exanthema (Rash) 03/2008 - 08/2006
3	Headache (Headaches) 11/2007 - 04/2002
3	Rhinitis 11/2007 - 04/2002
3	Edema (Dropsy) 11/2007 - 04/2002
2	Asthenia 01/2022 - 04/2002
2	Inflammation (Inflammations) 12/2020 - 12/2004
2	Cancer Pain 01/2018 - 09/2013
2	Bone Diseases (Bone Disease) 01/2018 - 01/2012
2	Fowlpox 09/2015 - 01/2015

Drug/Important Bio-Agent (IBA)

49	AndrogensIBA 12/2021 - 03/2002
42	Docetaxel (Taxotere)FDA Link 01/2021 - 03/2002
36	Hormones (Hormone)IBA 10/2022 - 02/2003
27	Prostate-Specific Antigen (Semenogelase)IBA 01/2021 - 04/2002
17	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 01/2011
13	abirateroneIBA 01/2022 - 04/2014
13	enzalutamideIBA 01/2022 - 09/2014
12	Testosterone (Sustanon)FDA Link 12/2021 - 03/2008
12	Biomarkers (Surrogate Marker)IBA 01/2018 - 10/2003
11	Pharmaceutical PreparationsIBA 10/2020 - 04/2002
11	Biological ProductsIBA 01/2019 - 01/2004
10	Sunitinib (Sutent)FDA Link 10/2019 - 09/2011
10	Histone Deacetylase InhibitorsIBA 12/2017 - 02/2005
10	AtrasentanIBA 01/2017 - 04/2002
7	Bevacizumab (Avastin)FDA Link 10/2020 - 01/2013
7	Prednisone (Sone)FDA LinkGeneric 01/2019 - 05/2005
6	AntigensIBA 10/2022 - 03/2012
6	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 02/2005
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2017 - 05/2002
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 09/2006
5	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 09/2003
5	Histone Deacetylases (Histone Deacetylase)IBA 03/2017 - 09/2006
5	TOR Serine-Threonine KinasesIBA 10/2013 - 06/2010
4	taxaneIBA 01/2022 - 08/2015
4	Alkaline PhosphataseIBA 05/2021 - 03/2003
4	Androgen Antagonists (Antiandrogens)IBA 01/2020 - 02/2011
4	LigandsIBA 01/2019 - 01/2012
4	Vorinostat FDA Link 03/2017 - 09/2013
4	VaccinesIBA 09/2015 - 05/2006
4	Ketoconazole (Nizoral)FDA LinkGeneric 04/2014 - 12/2003
4	Valproic Acid (Depakote)FDA LinkGeneric 10/2013 - 07/2007
4	Diphosphonates (Bisphosphonates)IBA 08/2013 - 08/2006
4	Endothelins (Endothelin)IBA 08/2013 - 05/2002
4	Endothelin Receptor AntagonistsIBA 08/2013 - 04/2002
3	Immune Checkpoint InhibitorsIBA 01/2021 - 06/2018
3	NivolumabIBA 01/2021 - 06/2018
3	IpilimumabIBA 01/2021 - 06/2018
3	Sorafenib (BAY 43-9006)FDA Link 10/2019 - 04/2013
3	Estramustine FDA Link 01/2018 - 03/2002
3	Interleukin-2 (IL2)IBA 12/2017 - 09/2011
3	Endothelin Receptors (Endothelin Receptor)IBA 12/2015 - 04/2002
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 09/2015 - 06/2006
3	Phosphotransferases (Kinase)IBA 02/2015 - 09/2007
3	tasquinimodIBA 11/2014 - 10/2011
3	EnzymesIBA 10/2014 - 01/2004
3	NucleosidesIBA 03/2011 - 12/2004
3	Histones (Histone)IBA 06/2008 - 07/2004
3	Endothelin A ReceptorIBA 11/2007 - 02/2003
2	CytokinesIBA 12/2021 - 12/2020
2	Analgesics (Analgesic Drugs)IBA 08/2021 - 09/2013
2	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 10/2016
2	Insulin (Novolin)FDA Link 01/2021 - 02/2006
2	Radium-223IBA 06/2020 - 01/2019
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 08/2007
2	Gemcitabine FDA Link 01/2020 - 09/2004
2	Vinblastine (Vinblastine Sulfate)FDA Link 01/2020 - 06/2016
2	Alanine Transaminase (SGPT)IBA 10/2019 - 03/2007
2	TubulinIBA 01/2019 - 04/2013
2	Messenger RNA (mRNA)IBA 07/2017 - 09/2014
2	Antineoplastic Agents (Antineoplastics)IBA 04/2017 - 10/2011
2	Taxoids (Taxanes)IBA 06/2016 - 10/2014
2	PROSTVACIBA 09/2015 - 01/2015

Therapy/Procedure

86	Therapeutics 04/2022 - 04/2002
64	Castration 04/2022 - 11/2007
20	Drug Therapy (Chemotherapy) 01/2020 - 12/2002
12	Prostatectomy (Retropubic Prostatectomy) 01/2021 - 12/2004
8	Immunotherapy 06/2016 - 06/2006
5	Radiotherapy 01/2021 - 03/2007
3	Drug Tapering 01/2016 - 02/2006
2	Neoadjuvant Therapy 01/2020 - 04/2016
2	Investigational Therapies (Experimental Therapy) 10/2018 - 03/2012
2	Nephrectomy 01/2016 - 12/2012